Real Madrid have been hit by a wave of injury setbacks, with defenders Ferland Mendy and David Alaba both facing potential season-ending injuries, the Spanish club confirmed on Tuesday, Reuters reported.

Mendy suffered a rupture in his right thigh during the Copa del Rey final loss to Barcelona, the Spanish club said on Tuesday.

Local media reports said Mendy could face up to a month on the sidelines in the latest setback for the France left back, who has already missed several weeks due to multiple injuries this season.

"Following tests carried out on our player Ferland Mendy... he has been diagnosed with a rupture of the proximal tendon of the anterior rectus in the right quadriceps," Real said in a statement, according to Reuters.