Israel and Iran kept up their attacks, killing and wounding civilians and raising concern among world leaders at a G7 meeting in Canada this week that the biggest battle between the two old enemies could lead to a broader regional conflict, Reuters reported.

The Iranian death toll in four days of Israeli strikes, carried out with the declared aim of wiping out Iran’s nuclear and ballistic missile programs, had reached at least 224, with 90% of the casualties reported to be civilians, an Iranian health ministry spokesperson said.

Early on Monday, the Israeli military said it had detected more missiles launched from Iran towards Israel.

"At this time, the (Israeli Air Force) is operating to intercept and strike where necessary to eliminate the threat," the Israeli Defence Forces said. Live video footage showed several missiles over Tel Aviv and Reuters witnesses said explosions could be heard there and over Jerusalem, according to Reuters.

At least 10 people in Israel, including children, have been killed so far, according to authorities there.