Iran and Israel launched new missile strikes at each other on Wednesday as the air war between the two longtime enemies entered a sixth day despite a call from U.S. President Donald Trump for Iran's unconditional surrender, Reuters reported.

The Israeli military said two barrages of Iranian missiles were launched toward Israel in the first two hours of Wednesday morning. Explosions were heard over Tel Aviv.

Israel told residents in the area of Tehran to evacuate so its air force could strike Iranian military installations. Iranian news websites said explosions were heard in Tehran and the city of Karaj west of the capital.

Trump warned on social media on Tuesday that U.S. patience was wearing thin. While he said there was no intention to kill Iran's leader "for now," his comments suggested a more aggressive stance toward Iran as he weighs whether to deepen U.S. involvement, according to Reuters.