What is the difference between a living body and a dead one? In the dead, similar to the living, all the organs are precisely where they are supposed to be (except if the dead had endured significant damage in any of the organs or bones). The difference is the dead are not breathing; that is to say, the food is not being oxidized, energy is not created; hence, all the major biological processes are stagnant. But what truly makes us breathe? Why do we breathe? What makes life live? Hypothetically, if we configure a body from scratch, engineering every organ, every bone, and every piece of flesh precisely where they are supposed to be, do we create a fully functional living body? No. According to the eastern philosophy based on Sri Isopanisad, too, an ‘organic whole’ cannot arise from parts that have to be assembled. That process can only produce inorganic, mechanical, or chemical processes, not living organisms. Hence, even if we successfully integrate all the organs, flesh, and bones to engineer a body, an entity that is missing what truly makes life live is consciousness. In this article, I’ll subtly try to answer the pressing mysteries about the origin of consciousness using a molecular and cellular perspective.
A conscious cell
All human beings, and other living beings, have an ancestral cell that, some billion years ago, was divided into two; that is to say, the ancestral cell passed on its genetic information onto another one, and so on and so forth, forming organs, systems, and organisms. It can be hypothesized that the energy, or an entity, that someday drove the passing of information from one cell to another is the same energy (consciousness) that today enables us to think, perceive, learn, and live. Moreover, cells can interpret chemical messages, communicate via cell signaling, regulate internal functions, and perform programmed cell death, illustrating coordinated, intelligent responses to environmental stimuli. These behaviors suggest that consciousness and cognition have biological bases at the cellular and molecular levels. According to Eshel Ben-Jacob, a pioneer in the study of bacterial intelligence and social behavior of bacteria, consciousness also exists in most primitive organisms without a brain, like plants and unicellular organisms like bacteria. Jacobs states that unicellular organisms also display learning, memory, anticipation, risk management, and other aspects of cognitive behavior. These examples, ultimately, provide more legitimacy to the idea that cells are sentient beings.
Cell consciousness, evolution, and Darwinism
The notion that consciousness could emerge from cells challenges neo-Darwinism and the theory of evolution. Darwinism suggests that some random changes in the genetic code within DNA give rise to a genetic diversity that undergoes a natural selection pressure within the environment; and upon surviving the selection pressure, organisms and species adapt, change, and evolve. If the cells are conscious on their own, it can be hypothesized that mutation could be a conscious act—and not just a ‘random’ change in the genetic code. James A. Shapiro, a molecular biologist at the University of Chicago and the author of the book Evolution: A View from the 21st Century, states that “A shift from thinking about gradual selection of localized random changes to sudden genome restructuring by sensory network-influenced cell systems is a major conceptual change. It replaces the “invisible hands” of geological time and natural selection with cognitive networks and cellular functions for self-modification. The emphasis is systemic rather than atomistic and information-based rather than stochastic.”
Moreover, Richard Dawkins, in The Selfish Gene, also argues that organisms are merely a survival machine for the genes that created cells, synthesized proteins, and formed sophisticated membranes and cellular mechanisms to eventually create bodies and minds to protect themselves and their legacies.
Consciousness and quantum mechanics
As a kid, I was always confused about what the fundamental particles of nature were. In chemistry, I learned that electrons, protons, and neutrons were the fundamental particles. In physics, I learned that protons and neutrons can further be divided into quarks. And in biology, I learned that cells are the fundamental building blocks of life. I never really understood the difference between an atom and a cell. It was not until high school that I realized that cells that contain a nucleus, mitochondria, cytoplasm, ribosomes, and vacuoles can further be divided into proteins, water molecules, and other organic compounds that are fundamentally made up of particles like electrons and quarks. So, it can be hypothesized that the nucleus that contains DNA, which works to synthesize proteins with the help of RNA and also triggers the process of cell division (nuclei are the brains of cells), is guided by the quantum phenomena that take place deep within the atoms that form these cell bodies.
There have been numerous theories and pieces of evidence that have worked to find connections between quantum theories and consciousness. One such theory is the Orch OR (Orchestrated Objective Reduction) theory, which posits that tubulin proteins within neuronal microtubules engage in quantum computations via superposition and objective reduction events that generate discrete moments of conscious awareness.
Furthermore, Goodman et al. state that the theoretical models suggest that weak force interactions and electron neutrino exchanges might also support long-range quantum coherence across cellular assemblies, thereby linking quantum mechanics to large-scale neural synchrony. These perspectives collectively emphasize that quantum-level biomolecular interactions provide mechanisms for the integration of information across both spatial and temporal scales, which is essential for the emergent property of consciousness.
In summary, these theories and ideas give strength to the fact that consciousness arises from the cells, not from the brain. Evidence from cellular biology indicates that individual cells exhibit rudimentary forms of awareness through membrane dynamics, laying the foundation for conscious processes. Ultimately, the synthesis of molecular, quantum, and integrative theories provides a robust framework for understanding how consciousness could emerge from the fundamental interactions of biomolecules.
Chirag Timilsina
