Global airlines suspendedflights across the Middle East on Saturday after the United States and Israel launched strikes on Iran, plunging the region into a renewed military confrontation, Reuters reported. 

Flight maps showed the airspace over Iran, Iraq, Kuwait, Israel and Bahrain virtually empty as Israel said it struck Iran and the U.S. military initiated a series of strikes against targets in the country. Iran retaliated with a salvo of missiles.

Airlines have cancelled almost 40% of flights to Israel and 6.7% of flights to the broader region on Saturday, according to preliminary Cirium data, according to Reuters.