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The government of Nepal has expressed deep concern over the evolving situation in the Middle East, saying that it is closely monitoring the developments. 

In a statement issued by the Ministry of Foreign Affairs on Sunday, Nepal called on all sides to exercise maximum restraint amid rising regional tensions. 

The government emphasized that differences should be resolved through diplomacy and dialogue rather than military action.

Furthermore, Nepal stressed that the sovereignty and territorial integrity of all states must be respected in line with the UN Charter and international law. 

Nepal underscored the need to uphold the rules-based international order and the responsibility to maintain global peace and security. 

Pakistani police fired tear gas on Sunday to scatter protesters who breached the outer wall of the U.S. consulate in the southern city of Karachi following news of U.S. and Israeli strikes on Iran that killed Supreme Leader Ayatollah Ali Khamenei, Reuters reported. 

Pro-Iranian protesters also gathered outside the Green Zone in the Iraqi capital Baghdad, where the U.S. Embassy is located.

In Karachi, protesters had been pushed back from the consulate, a spokesman for the local government said. A Reuters reporter heard sounds of gunfire and video footage from the scenes showed burning vehicles outside the consulate's main gate, according to Reuters. 

A powerful explosion rocked Tehran on Sunday as the Israeli military said it was targeting the “heart” of the city. The blast sent a towering plume of smoke into the sky and shook surrounding neighborhoods, according to AP.

It was not immediately clear what specific site had been struck. The explosion appeared centered in an area housing Iran’s police headquarters and facilities linked to state television.

Israel said it was striking key targets in central Tehran after clearing what it described as a path to the capital a day earlier. The attack marks a sharp escalation in hostilities between Israel and Iran, AP reported.

A near-total internet blackout continued across Iran on Sunday morning, marking the second day of escalating conflict involving the US and Israel, AP wrote. Monitoring groups reported that connectivity remained severely restricted nationwide. 

Internet watchdog NetBlocks said online access had flatlined at just 1 percent of normal levels. The disruption has left millions unable to communicate or access information as tensions continue to rise, according to AP.

Authorities in Iran have frequently imposed internet and international call restrictions since nationwide anti-government protests began earlier this year. The latest blackout adds to concerns over transparency and access to information during the unfolding crisis.

Japan on Sunday said Iran must not be allowed to develop nuclear weapons, calling for restraint and dialogue. Chief Cabinet Secretary Minoru Kihara said Tokyo has consistently supported talks between the United States and Iran to resolve tensions.

According to AP, Kihara urged Iran to halt nuclear weapons development and other actions that could destabilize the region. He stopped short of openly backing the recent US attack on Iran, emphasizing instead the importance of diplomacy and de-escalation.

AP reported, Defense Minister Shinjiro Koizumi said Japan is preparing to dispatch troops to help evacuate about 200 Japanese nationals still in Iran. He provided no further operational details but said Tokyo will work with the international community to maintain regional stability.

At least six people were killed after hundreds of protesters stormed the US Consulate in Karachi on Sunday, according to AP. Police said clashes broke out as officers tried to control the crowd. Several others were reported injured before the situation was brought under control.

The unrest followed joint strikes by the United States and Israel on Iran. It has triggered outrage and protests in several areas. Authorities later dispersed the demonstrators around the consulate. AP reported, security was tightened across the city to prevent further violence. Tensions remain high amid fears of wider regional escalation.

China has urged for an immediate ceasefire after the US and Israel’s strikes on Iran. China’s Ministry of Foreign Affairs expressed concern over the strikes and urged all sides to avoid escalation and to resume dialogue and negotiation. In a statement yesterday, the ministry said Iran’s sovereignty, security and territorial integrity should be respected, Reuters reported. 

China’s state-run news agency called Washington’s use of military coercion was a flagrant violation of the purposes and principles of the United Nations Charter and a departure from fundamental norms of international relations. China’s embassy in Israel has issued a notice advising Chinese citizens in Israel to evacuate to safer areas within the country as soon as possible or to leave for Egypt via the Taba border crossing. China’s foreign ministry also urged Chinese citizens in Iran to leave as soon as possible, listing four land routes to Azerbaijan, Armenia, Turkey and Iraq.

Israel said it had launched another wave of strikes on Iran on Sunday, as Iranians faced uncertainty after the killing of their supreme leader in US and Israeli attacks that threatened to destabilize the wider Middle East, Reuters reported. 

Hours after the United States and Israel said that an air strike killed Ayatollah Ali Khamenei as part of the most ambitious series of attacks on Iran in decades, Iranian state media confirmed the 86-year-old leader’s death on Saturday.

US President Donald Trump said the air strikes on Iranian targets were aimed at ending a decades-long threat from Iran and ensuring it could not develop a nuclear weapon as he sought to justify a risky gambit that seemed to go against his professed opposition to American involvement in complex overseas conflicts, according to Reuters.